... Complexes 1 1 1 1 Dengue 1 virus Neutralizing antibody to Dengue 1 virus Non-neutralizing antibody 1 Complex formed by neutralizing antibody and virus ... Dengue ppt Kenneth Munoz. Fully immature dengue virus particles contain a full complement of prM proteins and are non-infectious, whereas all prM proteins are cleaved in fully mature virus particles. Forty percent of the world’s population, about 3 billion people, live in areas with a risk of dengue. Mosquito life cycle Aedes aegypti Adult Eggs Larva Pupa The Aedes mosquitoes have 4 life stages: egg, larva, pupa and adult. Nevertheless, scientists' understanding of dengue virus may be simplistic, as rather than distinct antigenic groups, a continuum appears to exist. The dengue virus life cycle begins with infection of a human or nonhuman primate host via an infected mosquito vector. Dengue is a mosquito-borne viral disease that has rapidly spread in all regions of WHO in recent years. Dengue virus is transmitted by female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, Ae. Dengue Fever (DF) Syndrome Dengue Hemorrhage Fever (DHF) Dengue Shock Syndrome With Unusual Hemorrhage Without Hemorrhage No Shock 11 Prevention. Although thrombocytopenia is typical of both mild and severe diseases, the mechanism triggering platelet reduction is incompletely understood. Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. The life cycle of the mosquito Aedes aegypti, an … PowerPoint Presentation: DF and DHF are caused by four dengue viruses-DEN 1, DEN2, DEN3, DEN4which are closely related antigenically . The adult life span can range from two weeks to a month depending on environmental conditions. The successful transmission of dengue virus from a human host to a mosquito vector requires a complex set of factors to align. Depending on students’ background, it may be helpful to pause the animation at various points to discuss different structures or steps in the life cycle of dengue virus. Dengue virus, which causes the infectious disease dengue fever, is an RNA virus that infects immune system cells. Infection with one serotype provides life long immunity to that virus but not to others. Dengue virus (DENV 1-4) represents a major emerging arthropod-borne pathogen. Because Dengue fever is spread by a virus, there is no specific medicine or antibiotic to treat it. He has also done FCCS course and is certified Advance Cardiac Life support (ACLS) and Basic Life Support (BLS) provider by American Heart Association. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease. Dengue Virus Life Cycle. Dengue viruses are spread to people through the bite of an infected Aedes species (Ae. Eventually, enough proteins are made to assemble new viruses that can bud off and infect other cells. The life cycle of Aedes aegypti can be completed within one-and-a-half to three weeks (see figure 1). It is becoming increasingly important to improve our understanding of the parameters that shape the human to mosquito component of the transmission cycle so that vaccines and therapeutic antivirals can be fully evaluated and epidemiological models … High vector density combined with high population density in urban areas has allowed dengue virus to get a strong foothold in many of the world’s over-crowded tropical cities [6]. Pupae develop into adult flying mosquitoes in … aegypti or Ae. albopictus) mosquito.Dengue is common in more than 100 countries around the world. Dengue virus (DENV) infection causes ∼200 million cases of severe flulike illness annually, escalating to life-threatening hemorrhagic fever or shock syndrome in ∼500 000. All four DENV serotypes are prevalent in the (sub) tropical regions of the world and infect 50–100 million individuals annually.